000 01204 a2200289 4500
005 20250517225710.0
264 0 _c20191004
008 201910s 0 0 eng d
022 _a1521-0103
024 7 _a10.1124/jpet.118.250134
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Xiaobing
245 0 0 _aRole of Interstitial Fluid Turnover on Target Suppression by Therapeutic Biologics Using a Minimal Physiologically Based Pharmacokinetic Model.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_c10 2018
300 _a1-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aBiological Products
_xmetabolism
650 0 4 _aExtracellular Fluid
_xmetabolism
650 0 4 _aModels, Biological
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aTissue Distribution
650 0 4 _aTumor Necrosis Factor-alpha
_xmetabolism
700 1 _aJusko, William J
700 1 _aCao, Yanguang
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 367
_gno. 1
_gp. 1-8
856 4 0 _uhttps://doi.org/10.1124/jpet.118.250134
_zAvailable from publisher's website
999 _c28626473
_d28626473