000			02079 a2200601 4500
005			20250517224140.0
264		0	_c20190801
008			201908s 0 0 eng d
022			_a1432-0843
024	7		_a10.1007/s00280-018-3619-3 _2doi
040			_aNLM _beng _cNLM
100	1		_aSehdev, Amikar
245	0	0	_aA pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors. _h[electronic resource]
260			_bCancer chemotherapy and pharmacology _c08 2018
300			_a309-317 p. _bdigital
500			_aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAdolescent
650	0	4	_aAdult
650	0	4	_aAged
650	0	4	_aAged, 80 and over
650	0	4	_aAntineoplastic Combined Chemotherapy Protocols _xadministration & dosage
650	0	4	_aBiomarkers, Tumor _xblood
650	0	4	_aDrug Synergism
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aLeukocytes, Mononuclear _xdrug effects
650	0	4	_aMale
650	0	4	_aMetformin _xadministration & dosage
650	0	4	_aMiddle Aged
650	0	4	_aNeoplasms _xblood
650	0	4	_aPhosphorylation
650	0	4	_aPilot Projects
650	0	4	_aRibosomal Protein S6 Kinases, 70-kDa _xblood
650	0	4	_aSirolimus _xadministration & dosage
650	0	4	_aTOR Serine-Threonine Kinases _xantagonists & inhibitors
650	0	4	_aYoung Adult
700	1		_aKarrison, Theodore
700	1		_aZha, Yuanyuan
700	1		_aJanisch, Linda
700	1		_aTurcich, Michelle
700	1		_aCohen, Ezra E W
700	1		_aMaitland, Michael
700	1		_aPolite, Blase N
700	1		_aGajewski, Thomas F
700	1		_aSalgia, Ravi
700	1		_aPinto, Navin
700	1		_aBissonnette, Marc B
700	1		_aFleming, Gini F
700	1		_aRatain, Mark J
700	1		_aSharma, Manish R
773	0		_tCancer chemotherapy and pharmacology _gvol. 82 _gno. 2 _gp. 309-317
856	4	0	_uhttps://doi.org/10.1007/s00280-018-3619-3 _zAvailable from publisher's website
999			_c28574689 _d28574689