| 000 | 01591 a2200421 4500 | ||
|---|---|---|---|
| 005 | 20250517223430.0 | ||
| 264 | 0 | _c20181211 | |
| 008 | 201812s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.118.081539 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aBapiro, Tashinga E | |
| 245 | 0 | 0 |
_aComplete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor Degrader. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _c09 2018 |
||
| 300 |
_a1268-1276 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 |
_aCinnamates _xmetabolism |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP2C8 _xmetabolism |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP2C8 Inhibitors _xmetabolism |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aIndoles _xmetabolism |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xdrug effects |
| 650 | 0 | 4 |
_aReceptors, Estrogen _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aSubstrate Specificity _xdrug effects |
| 700 | 1 | _aSykes, Andy | |
| 700 | 1 | _aMartin, Scott | |
| 700 | 1 | _aDavies, Michael | |
| 700 | 1 | _aYates, James W T | |
| 700 | 1 | _aHoch, Matthias | |
| 700 | 1 | _aRollison, Helen E | |
| 700 | 1 | _aJones, Barry | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 46 _gno. 9 _gp. 1268-1276 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.118.081539 _zAvailable from publisher's website |
| 999 |
_c28549003 _d28549003 |
||