000 01625 a2200433 4500
005 20250517222224.0
264 0 _c20190212
008 201902s 0 0 eng d
022 _a1083-351X
024 7 _a10.1074/jbc.RA118.003650
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRege, Nischay K
245 0 0 _aStructure-based stabilization of insulin as a therapeutic protein assembly via enhanced aromatic-aromatic interactions.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_c07 2018
300 _a10895-10910 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAmino Acid Sequence
650 0 4 _aAmino Acids, Aromatic
_xchemistry
650 0 4 _aAnimals
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDiabetes Mellitus, Experimental
_xprevention & control
650 0 4 _aDimerization
650 0 4 _aInsulin
_xchemistry
650 0 4 _aMale
650 0 4 _aModels, Molecular
650 0 4 _aProtein Binding
650 0 4 _aProtein Conformation
650 0 4 _aRats
650 0 4 _aRats, Inbred Lew
650 0 4 _aReceptor, Insulin
_xmetabolism
700 1 _aWickramasinghe, Nalinda P
700 1 _aTustan, Alisar N
700 1 _aPhillips, Nelson F B
700 1 _aYee, Vivien C
700 1 _aIsmail-Beigi, Faramarz
700 1 _aWeiss, Michael A
773 0 _tThe Journal of biological chemistry
_gvol. 293
_gno. 28
_gp. 10895-10910
856 4 0 _uhttps://doi.org/10.1074/jbc.RA118.003650
_zAvailable from publisher's website
999 _c28508833
_d28508833