000			02195 a2200661 4500
005			20250517222221.0
264		0	_c20190624
008			201906s 0 0 eng d
022			_a1540-9538
024	7		_a10.1084/jem.20171960 _2doi
040			_aNLM _beng _cNLM
100	1		_aSaei, Azad
245	0	0	_aLoss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies. _h[electronic resource]
260			_bThe Journal of experimental medicine _c07 2018
300			_a1913-1928 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aCell Line, Tumor
650	0	4	_aDown-Regulation
650	0	4	_aDrug Resistance, Neoplasm
650	0	4	_aF-Box-WD Repeat-Containing Protein 7 _xmetabolism
650	0	4	_aGene Deletion
650	0	4	_aGlycine _xanalogs & derivatives
650	0	4	_aHEK293 Cells
650	0	4	_aHumans
650	0	4	_aMAP Kinase Signaling System
650	0	4	_aMelanoma _xdrug therapy
650	0	4	_aMice
650	0	4	_aPrognosis
650	0	4	_aProtein Stability
650	0	4	_aProteolysis
650	0	4	_aProto-Oncogene Proteins B-raf _xmetabolism
650	0	4	_aSulfones _xpharmacology
650	0	4	_aUbiquitin Thiolesterase _xdeficiency
650	0	4	_aVemurafenib _xpharmacology
700	1		_aPalafox, Marta
700	1		_aBenoukraf, Touati
700	1		_aKumari, Nishi
700	1		_aJaynes, Patrick William
700	1		_aIyengar, Prasanna Vasudevan
700	1		_aMuñoz-Couselo, Eva
700	1		_aNuciforo, Paolo
700	1		_aCortés, Javier
700	1		_aNötzel, Christopher
700	1		_aKumarakulasinghe, Nesaretnam Barr
700	1		_aRichard, John Lalith Charles
700	1		_aBin Adam Isa, Zul Fazreen
700	1		_aPang, Brendan
700	1		_aGuzman, Marta
700	1		_aSiqin, Zhou
700	1		_aYang, Henry
700	1		_aTam, Wai Leong
700	1		_aSerra, Violeta
700	1		_aEichhorn, Pieter Johan Adam
773	0		_tThe Journal of experimental medicine _gvol. 215 _gno. 7 _gp. 1913-1928
856	4	0	_uhttps://doi.org/10.1084/jem.20171960 _zAvailable from publisher's website
999			_c28508670 _d28508670