000 01668 a2200433 4500
005 20250517222030.0
264 0 _c20181018
008 201810s 0 0 eng d
022 _a2169-141X
024 7 _a10.1080/21691401.2018.1476375
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGuo, Chen
245 0 0 _aLong term safety and immunological effects of a nanobiotherapeutic, bovine poly-[hemoglobin-catalase-superoxide dismutase-carbonic anhydrase], after four weekly 5% blood volume top-loading followed by a challenge of 30% exchange transfusion.
_h[electronic resource]
260 _bArtificial cells, nanomedicine, and biotechnology
_cNov 2018
300 _a1349-1363 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aArterial Pressure
_xdrug effects
650 0 4 _aBlood Substitutes
_xadverse effects
650 0 4 _aBlood Transfusion
650 0 4 _aBlood Volume
650 0 4 _aBody Weight
_xdrug effects
650 0 4 _aCarbonic Anhydrases
_xchemistry
650 0 4 _aCatalase
_xchemistry
650 0 4 _aCattle
650 0 4 _aComplement C3a
_xmetabolism
650 0 4 _aHemoglobins
_xchemistry
650 0 4 _aHumans
650 0 4 _aImmunoglobulin G
_xblood
650 0 4 _aImmunoglobulin M
_xblood
650 0 4 _aNanomedicine
_xmethods
650 0 4 _aProtein Multimerization
650 0 4 _aRats
650 0 4 _aSafety
650 0 4 _aSuperoxide Dismutase
_xchemistry
700 1 _aChang, Thomas Ming Swi
773 0 _tArtificial cells, nanomedicine, and biotechnology
_gvol. 46
_gno. 7
_gp. 1349-1363
856 4 0 _uhttps://doi.org/10.1080/21691401.2018.1476375
_zAvailable from publisher's website
999 _c28501862
_d28501862