000 | 01597 a2200409 4500 | ||
---|---|---|---|
005 | 20250512022134.0 | ||
264 | 0 | _c19880907 | |
008 | 198809s 0 0 eng d | ||
022 | _a0027-8424 | ||
024 | 7 |
_a10.1073/pnas.85.15.5478 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aFraser, C M | |
245 | 0 | 0 |
_aSite-directed mutagenesis of human beta-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase. _h[electronic resource] |
260 |
_bProceedings of the National Academy of Sciences of the United States of America _cAug 1988 |
||
300 |
_a5478-82 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 |
_aAdenylyl Cyclases _xmetabolism |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAsparagine _xgenetics |
650 | 0 | 4 |
_aAspartic Acid _xgenetics |
650 | 0 | 4 | _aBase Sequence |
650 | 0 | 4 | _aBinding, Competitive |
650 | 0 | 4 |
_aCatecholamines _xmetabolism |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 | _aGene Expression Regulation |
650 | 0 | 4 |
_aGuanine Nucleotides _xpharmacology |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMolecular Sequence Data |
650 | 0 | 4 | _aMutation |
650 | 0 | 4 |
_aReceptors, Adrenergic, beta _xgenetics |
650 | 0 | 4 | _aSequence Homology, Nucleic Acid |
700 | 1 | _aChung, F Z | |
700 | 1 | _aWang, C D | |
700 | 1 | _aVenter, J C | |
773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 85 _gno. 15 _gp. 5478-82 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.85.15.5478 _zAvailable from publisher's website |
999 |
_c2846527 _d2846527 |