000 02116 a2200625 4500
005 20250517220042.0
264 0 _c20191112
008 201911s 0 0 eng d
022 _a1097-6825
024 7 _a10.1016/j.jaci.2018.04.030
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aEdwards, Emily S J
245 0 0 _aActivating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity.
_h[electronic resource]
260 _bThe Journal of allergy and clinical immunology
_c01 2019
300 _a276-291.e6 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aB-Lymphocytes
_ximmunology
650 0 4 _aCD8-Positive T-Lymphocytes
_ximmunology
650 0 4 _aCell Differentiation
_xgenetics
650 0 4 _aCellular Senescence
_xgenetics
650 0 4 _aChild
650 0 4 _aChild, Preschool
650 0 4 _aClass I Phosphatidylinositol 3-Kinases
_xgenetics
650 0 4 _aEpstein-Barr Virus Infections
_xgenetics
650 0 4 _aGain of Function Mutation
650 0 4 _aGenetic Diseases, Inborn
_xgenetics
650 0 4 _aHerpesvirus 4, Human
_ximmunology
650 0 4 _aHumans
650 0 4 _aImmunologic Surveillance
_xgenetics
650 0 4 _aKiller Cells, Natural
_ximmunology
650 0 4 _aMale
650 0 4 _aMiddle Aged
700 1 _aBier, Julia
700 1 _aCole, Theresa S
700 1 _aWong, Melanie
700 1 _aHsu, Peter
700 1 _aBerglund, Lucinda J
700 1 _aBoztug, Kaan
700 1 _aLau, Anthony
700 1 _aGostick, Emma
700 1 _aPrice, David A
700 1 _aO'Sullivan, Michael
700 1 _aMeyts, Isabelle
700 1 _aChoo, Sharon
700 1 _aGray, Paul
700 1 _aHolland, Steven M
700 1 _aDeenick, Elissa K
700 1 _aUzel, Gulbu
700 1 _aTangye, Stuart G
773 0 _tThe Journal of allergy and clinical immunology
_gvol. 143
_gno. 1
_gp. 276-291.e6
856 4 0 _uhttps://doi.org/10.1016/j.jaci.2018.04.030
_zAvailable from publisher's website
999 _c28429702
_d28429702