000			02360 a2200697 4500
005			20250517215525.0
264		0	_c20180705
008			201807s 0 0 eng d
022			_a1533-4406
024	7		_a10.1056/NEJMoa1804093 _2doi
040			_aNLM _beng _cNLM
100	1		_aRabe, Klaus F
245	0	0	_aEfficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma. _h[electronic resource]
260			_bThe New England journal of medicine _c06 2018
300			_a2475-2485 p. _bdigital
500			_aPublication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650	0	4	_aAdministration, Oral
650	0	4	_aAdolescent
650	0	4	_aAdult
650	0	4	_aAnti-Asthmatic Agents _xadverse effects
650	0	4	_aAntibodies, Monoclonal _xadverse effects
650	0	4	_aAntibodies, Monoclonal, Humanized
650	0	4	_aAsthma _xclassification
650	0	4	_aChild
650	0	4	_aDouble-Blind Method
650	0	4	_aDrug Therapy, Combination
650	0	4	_aEosinophilia _xchemically induced
650	0	4	_aFemale
650	0	4	_aForced Expiratory Volume _xdrug effects
650	0	4	_aGlucocorticoids _xadministration & dosage
650	0	4	_aHumans
650	0	4	_aInjections, Subcutaneous _xadverse effects
650	0	4	_aIntention to Treat Analysis
650	0	4	_aLogistic Models
650	0	4	_aMale
650	0	4	_aMiddle Aged
650	0	4	_aReceptors, Interleukin-4 _xantagonists & inhibitors
650	0	4	_aYoung Adult
700	1		_aNair, Parameswaran
700	1		_aBrusselle, Guy
700	1		_aMaspero, Jorge F
700	1		_aCastro, Mario
700	1		_aSher, Lawrence
700	1		_aZhu, Hongjie
700	1		_aHamilton, Jennifer D
700	1		_aSwanson, Brian N
700	1		_aKhan, Asif
700	1		_aChao, Jingdong
700	1		_aStaudinger, Heribert
700	1		_aPirozzi, Gianluca
700	1		_aAntoni, Christian
700	1		_aAmin, Nikhil
700	1		_aRuddy, Marcella
700	1		_aAkinlade, Bolanle
700	1		_aGraham, Neil M H
700	1		_aStahl, Neil
700	1		_aYancopoulos, George D
700	1		_aTeper, Ariel
773	0		_tThe New England journal of medicine _gvol. 378 _gno. 26 _gp. 2475-2485
856	4	0	_uhttps://doi.org/10.1056/NEJMoa1804093 _zAvailable from publisher's website
999			_c28411817 _d28411817