| 000 | 01762 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250517214225.0 | ||
| 264 | 0 | _c20191003 | |
| 008 | 201910s 0 0 eng d | ||
| 022 | _a1573-8744 | ||
| 024 | 7 |
_a10.1007/s10928-018-9589-6 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aCheung, S Y A | |
| 245 | 0 | 0 |
_aA tutorial on model informed approaches to cardiovascular safety with focus on cardiac repolarisation. _h[electronic resource] |
| 260 |
_bJournal of pharmacokinetics and pharmacodynamics _c06 2018 |
||
| 300 |
_a365-381 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBlood Pressure _xdrug effects |
| 650 | 0 | 4 |
_aCardiovascular Diseases _xchemically induced |
| 650 | 0 | 4 |
_aCardiovascular System _xdrug effects |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 |
_aDrug Discovery _xmethods |
| 650 | 0 | 4 | _aDrug Evaluation, Preclinical |
| 650 | 0 | 4 |
_aDrug-Related Side Effects and Adverse Reactions _xetiology |
| 650 | 0 | 4 | _aGuinea Pigs |
| 650 | 0 | 4 |
_aHeart Rate _xdrug effects |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMacaca mulatta |
| 650 | 0 | 4 |
_aPharmaceutical Preparations _xadministration & dosage |
| 650 | 0 | 4 | _aRabbits |
| 650 | 0 | 4 | _aRats |
| 700 | 1 | _aParkinson, J | |
| 700 | 1 | _aWählby-Hamrén, U | |
| 700 | 1 | _aDota, C D | |
| 700 | 1 | _aKragh, Å M | |
| 700 | 1 | _aBergenholm, L | |
| 700 | 1 | _aVik, T | |
| 700 | 1 | _aCollins, T | |
| 700 | 1 | _aArfvidsson, C | |
| 700 | 1 | _aPollard, C E | |
| 700 | 1 | _aTomkinson, H K | |
| 700 | 1 | _aHamrén, B | |
| 773 | 0 |
_tJournal of pharmacokinetics and pharmacodynamics _gvol. 45 _gno. 3 _gp. 365-381 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1007/s10928-018-9589-6 _zAvailable from publisher's website |
| 999 |
_c28367413 _d28367413 |
||