| 000 | 01644 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250517213138.0 | ||
| 264 | 0 | _c20190603 | |
| 008 | 201906s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/acs.jmedchem.7b01698 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aPant, Shishir M | |
| 245 | 0 | 0 |
_aDesign, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _c05 2018 |
||
| 300 |
_a4335-4347 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aBreast Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xchemistry |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aHigh-Throughput Screening Assays _xstandards |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 |
_aSerine Endopeptidases _xchemistry |
| 650 | 0 | 4 | _aTumor Cells, Cultured |
| 700 | 1 | _aMukonoweshuro, Amanda | |
| 700 | 1 | _aDesai, Bimbisar | |
| 700 | 1 | _aRamjee, Manoj K | |
| 700 | 1 | _aSelway, Christopher N | |
| 700 | 1 | _aTarver, Gary J | |
| 700 | 1 | _aWright, Adrian G | |
| 700 | 1 | _aBirchall, Kristian | |
| 700 | 1 | _aChapman, Timothy M | |
| 700 | 1 | _aTervonen, Topi A | |
| 700 | 1 | _aKlefström, Juha | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 61 _gno. 10 _gp. 4335-4347 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.7b01698 _zAvailable from publisher's website |
| 999 |
_c28333029 _d28333029 |
||