000 01768 a2200505 4500
005 20250517211823.0
264 0 _c20181227
008 201812s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2018.04.011
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAgarwal, Sameer
245 0 0 _aEvaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_c06 2018
300 _a1849-1852 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBinding Sites
650 0 4 _aDiabetes Mellitus, Type 2
_xdrug therapy
650 0 4 _aDrug Therapy, Combination
650 0 4 _aFemale
650 0 4 _aGlucagon-Like Peptide 1
_xmetabolism
650 0 4 _aHalf-Life
650 0 4 _aHumans
650 0 4 _aHypoglycemic Agents
_xchemistry
650 0 4 _aImidazoles
_xchemistry
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMolecular Docking Simulation
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aReceptors, G-Protein-Coupled
_xagonists
650 0 4 _aSitagliptin Phosphate
_xtherapeutic use
650 0 4 _aStructure-Activity Relationship
700 1 _aSasane, Santosh
700 1 _aKumar, Jeevan
700 1 _aDeshmukh, Prashant
700 1 _aBhayani, Hitesh
700 1 _aGiri, Poonam
700 1 _aGiri, Suresh
700 1 _aSoman, Shubhangi
700 1 _aKulkarni, Neelima
700 1 _aJain, Mukul
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 28
_gno. 10
_gp. 1849-1852
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2018.04.011
_zAvailable from publisher's website
999 _c28287958
_d28287958