000			01955 a2200613 4500
005			20250517211432.0
264		0	_c20180827
008			201808s 0 0 eng d
022			_a1476-4687
024	7		_a10.1038/s41586-018-0024-3 _2doi
040			_aNLM _beng _cNLM
100	1		_aRoerink, Sophie F
245	0	0	_aIntra-tumour diversification in colorectal cancer at the single-cell level. _h[electronic resource]
260			_bNature _c04 2018
300			_a457-462 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAntineoplastic Agents _xpharmacology
650	0	4	_aCell Proliferation
650	0	4	_aClone Cells _xdrug effects
650	0	4	_aColorectal Neoplasms _xdrug therapy
650	0	4	_aDNA Methylation
650	0	4	_aDNA Mutational Analysis
650	0	4	_aEvolution, Molecular
650	0	4	_aGene Expression Regulation, Neoplastic
650	0	4	_aHumans
650	0	4	_aIntestinal Mucosa _xmetabolism
650	0	4	_aIntestines _xcytology
650	0	4	_aMutation
650	0	4	_aMutation Rate
650	0	4	_aOrganoids _xcytology
650	0	4	_aSingle-Cell Analysis
650	0	4	_aTranscriptome
700	1		_aSasaki, Nobuo
700	1		_aLee-Six, Henry
700	1		_aYoung, Matthew D
700	1		_aAlexandrov, Ludmil B
700	1		_aBehjati, Sam
700	1		_aMitchell, Thomas J
700	1		_aGrossmann, Sebastian
700	1		_aLightfoot, Howard
700	1		_aEgan, David A
700	1		_aPronk, Apollo
700	1		_aSmakman, Niels
700	1		_avan Gorp, Joost
700	1		_aAnderson, Elizabeth
700	1		_aGamble, Stephen J
700	1		_aAlder, Chris
700	1		_avan de Wetering, Marc
700	1		_aCampbell, Peter J
700	1		_aStratton, Michael R
700	1		_aClevers, Hans
773	0		_tNature _gvol. 556 _gno. 7702 _gp. 457-462
856	4	0	_uhttps://doi.org/10.1038/s41586-018-0024-3 _zAvailable from publisher's website
999			_c28275742 _d28275742