000			02078 a2200553 4500
005			20250517211246.0
264		0	_c20191220
008			201912s 0 0 eng d
022			_a1557-3265
024	7		_a10.1158/1078-0432.CCR-17-3421 _2doi
040			_aNLM _beng _cNLM
100	1		_aBendell, Johanna C
245	0	0	_aA First-in-Human Phase 1 Study of LY3023414, an Oral PI3K/mTOR Dual Inhibitor, in Patients with Advanced Cancer. _h[electronic resource]
260			_bClinical cancer research : an official journal of the American Association for Cancer Research _c07 2018
300			_a3253-3262 p. _bdigital
500			_aPublication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650	0	4	_aAged
650	0	4	_aAged, 80 and over
650	0	4	_aAntineoplastic Agents _xadministration & dosage
650	0	4	_aBiomarkers
650	0	4	_aCombined Modality Therapy
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aMale
650	0	4	_aMiddle Aged
650	0	4	_aNeoplasm Metastasis
650	0	4	_aNeoplasm Staging
650	0	4	_aNeoplasms _xdiagnosis
650	0	4	_aPhosphoinositide-3 Kinase Inhibitors
650	0	4	_aProtein Kinase Inhibitors _xadministration & dosage
650	0	4	_aPyridines _xadministration & dosage
650	0	4	_aQuinolones _xadministration & dosage
650	0	4	_aRetreatment
650	0	4	_aTOR Serine-Threonine Kinases _xantagonists & inhibitors
650	0	4	_aTreatment Outcome
700	1		_aVarghese, Anna M
700	1		_aHyman, David M
700	1		_aBauer, Todd M
700	1		_aPant, Shubham
700	1		_aCallies, Sophie
700	1		_aLin, Ji
700	1		_aMartinez, Ricardo
700	1		_aWickremsinhe, Enaksha
700	1		_aFink, Aaron
700	1		_aWacheck, Volker
700	1		_aMoore, Kathleen N
773	0		_tClinical cancer research : an official journal of the American Association for Cancer Research _gvol. 24 _gno. 14 _gp. 3253-3262
856	4	0	_uhttps://doi.org/10.1158/1078-0432.CCR-17-3421 _zAvailable from publisher's website
999			_c28268691 _d28268691