000 01812 a2200481 4500
005 20250517211001.0
264 0 _c20190625
008 201906s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-17-1209
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLocal, Andrea
245 0 0 _aAPTO-253 Stabilizes G-quadruplex DNA, Inhibits MYC Expression, and Induces DNA Damage in Acute Myeloid Leukemia Cells.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_c06 2018
300 _a1177-1186 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Cycle Checkpoints
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCyclin-Dependent Kinase Inhibitor p21
_xgenetics
650 0 4 _aDNA Damage
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aG-Quadruplexes
_xdrug effects
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aLeukemia, Myeloid, Acute
_xgenetics
650 0 4 _aPhenanthrolines
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-myc
_xchemistry
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aStress, Physiological
_xdrug effects
700 1 _aZhang, Hongying
700 1 _aBenbatoul, Khalid D
700 1 _aFolger, Peter
700 1 _aSheng, Xia
700 1 _aTsai, Cheng-Yu
700 1 _aHowell, Stephen B
700 1 _aRice, William G
773 0 _tMolecular cancer therapeutics
_gvol. 17
_gno. 6
_gp. 1177-1186
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-17-1209
_zAvailable from publisher's website
999 _c28258751
_d28258751