000 | 02552 a2200685 4500 | ||
---|---|---|---|
005 | 20250517210516.0 | ||
264 | 0 | _c20180829 | |
008 | 201808s 0 0 eng d | ||
022 | _a1091-6490 | ||
024 | 7 |
_a10.1073/pnas.1801213115 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aChen, Shuliang | |
245 | 0 | 0 |
_aSAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways. _h[electronic resource] |
260 |
_bProceedings of the National Academy of Sciences of the United States of America _c04 2018 |
||
300 |
_aE3798-E3807 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 | _aCells, Cultured |
650 | 0 | 4 | _aDown-Regulation |
650 | 0 | 4 |
_aGene Expression Regulation _xdrug effects |
650 | 0 | 4 | _aGene Silencing |
650 | 0 | 4 | _aHEK293 Cells |
650 | 0 | 4 |
_aHIV _xphysiology |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aI-kappa B Kinase _xantagonists & inhibitors |
650 | 0 | 4 | _aImmunity, Innate |
650 | 0 | 4 |
_aInflammation _ximmunology |
650 | 0 | 4 |
_aInterferon Regulatory Factor-7 _xantagonists & inhibitors |
650 | 0 | 4 |
_aInterferon-alpha _xbiosynthesis |
650 | 0 | 4 |
_aMacrophages _ximmunology |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aNF-KappaB Inhibitor alpha _xmetabolism |
650 | 0 | 4 |
_aNF-kappa B _xmetabolism |
650 | 0 | 4 | _aPhosphorylation |
650 | 0 | 4 | _aProtein Processing, Post-Translational |
650 | 0 | 4 |
_aRecombinant Proteins _ximmunology |
650 | 0 | 4 |
_aSAM Domain and HD Domain-Containing Protein 1 _xphysiology |
650 | 0 | 4 |
_aSendai virus _xphysiology |
650 | 0 | 4 |
_aSignal Transduction _ximmunology |
650 | 0 | 4 | _aTHP-1 Cells |
650 | 0 | 4 |
_aVirus Diseases _ximmunology |
700 | 1 | _aBonifati, Serena | |
700 | 1 | _aQin, Zhihua | |
700 | 1 | _aSt Gelais, Corine | |
700 | 1 | _aKodigepalli, Karthik M | |
700 | 1 | _aBarrett, Bradley S | |
700 | 1 | _aKim, Sun Hee | |
700 | 1 | _aAntonucci, Jenna M | |
700 | 1 | _aLadner, Katherine J | |
700 | 1 | _aBuzovetsky, Olga | |
700 | 1 | _aKnecht, Kirsten M | |
700 | 1 | _aXiong, Yong | |
700 | 1 | _aYount, Jacob S | |
700 | 1 | _aGuttridge, Denis C | |
700 | 1 | _aSantiago, Mario L | |
700 | 1 | _aWu, Li | |
773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 115 _gno. 16 _gp. E3798-E3807 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.1801213115 _zAvailable from publisher's website |
999 |
_c28243323 _d28243323 |