000 01771 a2200505 4500
005 20250517205840.0
264 0 _c20190611
008 201906s 0 0 eng d
022 _a1872-7980
024 7 _a10.1016/j.canlet.2018.03.026
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aVan Heetvelde, Mattias
245 0 0 _aAccurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits.
_h[electronic resource]
260 _bCancer letters
_c07 2018
300 _a125-133 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aBRCA1 Protein
_xgenetics
650 0 4 _aBRCA2 Protein
_xgenetics
650 0 4 _aCohort Studies
650 0 4 _aDNA Copy Number Variations
650 0 4 _aDNA Methylation
650 0 4 _aEpigenesis, Genetic
650 0 4 _aFemale
650 0 4 _aGerm-Line Mutation
650 0 4 _aHereditary Breast and Ovarian Cancer Syndrome
_xgenetics
650 0 4 _aHumans
650 0 4 _aLoss of Heterozygosity
650 0 4 _aModels, Theoretical
650 0 4 _aPoint Mutation
650 0 4 _aPromoter Regions, Genetic
650 0 4 _aSequence Analysis, DNA
_xmethods
700 1 _aVan Bockstal, Mieke
700 1 _aPoppe, Bruce
700 1 _aLambein, Kathleen
700 1 _aRosseel, Toon
700 1 _aAtanesyan, Lilit
700 1 _aDeforce, Dieter
700 1 _aVan Den Berghe, Ivo
700 1 _aDe Leeneer, Kim
700 1 _aVan Dorpe, Jo
700 1 _aVral, Anne
700 1 _aClaes, Kathleen B M
773 0 _tCancer letters
_gvol. 425
_gp. 125-133
856 4 0 _uhttps://doi.org/10.1016/j.canlet.2018.03.026
_zAvailable from publisher's website
999 _c28219691
_d28219691