000 02575 a2200781 4500
005 20250517203609.0
264 0 _c20190520
008 201905s 0 0 eng d
022 _a1546-170X
024 7 _a10.1038/nm.4497
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDardaei, Leila
245 0 0 _aSHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.
_h[electronic resource]
260 _bNature medicine
_c05 2018
300 _a512-517 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnaplastic Lymphoma Kinase
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aCarcinoma, Non-Small-Cell Lung
_xenzymology
650 0 4 _aCell Line, Tumor
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xmetabolism
650 0 4 _aFemale
650 0 4 _aGene Rearrangement
_xgenetics
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xenzymology
650 0 4 _aMice, Nude
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProtein Tyrosine Phosphatase, Non-Receptor Type 11
_xantagonists & inhibitors
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aRNA, Small Interfering
_xmetabolism
650 0 4 _aSulfones
_xpharmacology
700 1 _aWang, Hui Qin
700 1 _aSingh, Manrose
700 1 _aFordjour, Paul
700 1 _aShaw, Katherine X
700 1 _aYoda, Satoshi
700 1 _aKerr, Grainne
700 1 _aYu, Kristine
700 1 _aLiang, Jinsheng
700 1 _aCao, Yichen
700 1 _aChen, Yan
700 1 _aLawrence, Michael S
700 1 _aLangenbucher, Adam
700 1 _aGainor, Justin F
700 1 _aFriboulet, Luc
700 1 _aDagogo-Jack, Ibiayi
700 1 _aMyers, David T
700 1 _aLabrot, Emma
700 1 _aRuddy, David
700 1 _aParks, Melissa
700 1 _aLee, Dana
700 1 _aDiCecca, Richard H
700 1 _aMoody, Susan
700 1 _aHao, Huaixiang
700 1 _aMohseni, Morvarid
700 1 _aLaMarche, Matthew
700 1 _aWilliams, Juliet
700 1 _aHoffmaster, Keith
700 1 _aCaponigro, Giordano
700 1 _aShaw, Alice T
700 1 _aHata, Aaron N
700 1 _aBenes, Cyril H
700 1 _aLi, Fang
700 1 _aEngelman, Jeffrey A
773 0 _tNature medicine
_gvol. 24
_gno. 4
_gp. 512-517
856 4 0 _uhttps://doi.org/10.1038/nm.4497
_zAvailable from publisher's website
999 _c28145761
_d28145761