000 01223 a2200349 4500
005 20250517203154.0
264 0 _c20190709
008 201907s 0 0 eng d
022 _a2050-084X
024 7 _a10.7554/eLife.32733
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWong, Yao Liang
245 0 0 _aThe small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes.
_h[electronic resource]
260 _beLife
_c02 2018
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetamides
_xmetabolism
650 0 4 _aCell Line
650 0 4 _aCyclohexylamines
_xmetabolism
650 0 4 _aEnzyme Activators
_xmetabolism
650 0 4 _aEukaryotic Initiation Factor-2B
_xgenetics
650 0 4 _aHumans
650 0 4 _aLeukoencephalopathies
_xgenetics
650 0 4 _aMutant Proteins
_xgenetics
650 0 4 _aNeuroprotective Agents
_xmetabolism
700 1 _aLeBon, Lauren
700 1 _aEdalji, Rohinton
700 1 _aLim, Hock Ben
700 1 _aSun, Chaohong
700 1 _aSidrauski, Carmela
773 0 _teLife
_gvol. 7
856 4 0 _uhttps://doi.org/10.7554/eLife.32733
_zAvailable from publisher's website
999 _c28130763
_d28130763