| 000 | 02299 a2200697 4500 | ||
|---|---|---|---|
| 005 | 20250517202219.0 | ||
| 264 | 0 | _c20190417 | |
| 008 | 201904s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/acs.jmedchem.7b01712 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aCrawford, James J | |
| 245 | 0 | 0 |
_aDiscovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _c03 2018 |
||
| 300 |
_a2227-2245 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAgammaglobulinaemia Tyrosine Kinase _xantagonists & inhibitors |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAnti-Inflammatory Agents _xpharmacokinetics |
| 650 | 0 | 4 |
_aArthritis, Experimental _xdrug therapy |
| 650 | 0 | 4 |
_aArthritis, Rheumatoid _xdrug therapy |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLupus Erythematosus, Systemic _xdrug therapy |
| 650 | 0 | 4 | _aMadin Darby Canine Kidney Cells |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aPiperazines _xpharmacokinetics |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xpharmacokinetics |
| 650 | 0 | 4 |
_aPyridones _xpharmacokinetics |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Inbred Lew |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 700 | 1 | _aJohnson, Adam R | |
| 700 | 1 | _aMisner, Dinah L | |
| 700 | 1 | _aBelmont, Lisa D | |
| 700 | 1 | _aCastanedo, Georgette | |
| 700 | 1 | _aChoy, Regina | |
| 700 | 1 | _aCoraggio, Melis | |
| 700 | 1 | _aDong, Liming | |
| 700 | 1 | _aEigenbrot, Charles | |
| 700 | 1 | _aErickson, Rebecca | |
| 700 | 1 | _aGhilardi, Nico | |
| 700 | 1 | _aHau, Jonathan | |
| 700 | 1 | _aKatewa, Arna | |
| 700 | 1 | _aKohli, Pawan Bir | |
| 700 | 1 | _aLee, Wendy | |
| 700 | 1 | _aLubach, Joseph W | |
| 700 | 1 | _aMcKenzie, Brent S | |
| 700 | 1 | _aOrtwine, Daniel F | |
| 700 | 1 | _aSchutt, Leah | |
| 700 | 1 | _aTay, Suzanne | |
| 700 | 1 | _aWei, BinQing | |
| 700 | 1 | _aReif, Karin | |
| 700 | 1 | _aLiu, Lichuan | |
| 700 | 1 | _aWong, Harvey | |
| 700 | 1 | _aYoung, Wendy B | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 61 _gno. 6 _gp. 2227-2245 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.7b01712 _zAvailable from publisher's website |
| 999 |
_c28100127 _d28100127 |
||