000 02200 a2200637 4500
005 20250517201224.0
264 0 _c20180622
008 201806s 0 0 eng d
022 _a1553-7374
024 7 _a10.1371/journal.ppat.1006850
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhang, Ning
245 0 0 _aHost-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.
_h[electronic resource]
260 _bPLoS pathogens
_c02 2018
300 _ae1006850 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aActivation, Metabolic
650 0 4 _aAldehyde Dehydrogenase
_xantagonists & inhibitors
650 0 4 _aAldehyde Oxidoreductases
_xantagonists & inhibitors
650 0 4 _aAmine Oxidase (Copper-Containing)
_xantagonists & inhibitors
650 0 4 _aAmino Acid Substitution
650 0 4 _aAnimals
650 0 4 _aBoron Compounds
_xchemistry
650 0 4 _aDrug Resistance
650 0 4 _aHigh-Throughput Screening Assays
650 0 4 _aHumans
650 0 4 _aModels, Biological
650 0 4 _aMolecular Structure
650 0 4 _aMutation
650 0 4 _aPhylogeny
650 0 4 _aProdrugs
_xchemistry
650 0 4 _aProtein Interaction Domains and Motifs
650 0 4 _aRNA Interference
650 0 4 _aRats
650 0 4 _aRecombinant Fusion Proteins
_xchemistry
650 0 4 _aRecombinant Proteins
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTrypanocidal Agents
_xchemistry
650 0 4 _aTrypanosoma brucei brucei
_xdrug effects
700 1 _aZoltner, Martin
700 1 _aLeung, Ka-Fai
700 1 _aScullion, Paul
700 1 _aHutchinson, Sebastian
700 1 _aDel Pino, Ricardo C
700 1 _aVincent, Isabel M
700 1 _aZhang, Yong-Kang
700 1 _aFreund, Yvonne R
700 1 _aAlley, Michael R K
700 1 _aJacobs, Robert T
700 1 _aRead, Kevin D
700 1 _aBarrett, Michael P
700 1 _aHorn, David
700 1 _aField, Mark C
773 0 _tPLoS pathogens
_gvol. 14
_gno. 2
_gp. e1006850
856 4 0 _uhttps://doi.org/10.1371/journal.ppat.1006850
_zAvailable from publisher's website
999 _c28068066
_d28068066