| 000 | 02920 a2200781 4500 | ||
|---|---|---|---|
| 005 | 20250517201054.0 | ||
| 264 | 0 | _c20180321 | |
| 008 | 201803s 0 0 eng d | ||
| 022 | _a1768-3254 | ||
| 024 | 7 |
_a10.1016/j.ejmech.2018.01.066 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aDias Viegas, Flávia Pereira | |
| 245 | 0 | 0 |
_aDesign, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates. _h[electronic resource] |
| 260 |
_bEuropean journal of medicinal chemistry _cMar 2018 |
||
| 300 |
_a48-65 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAcetylcholinesterase _xmetabolism |
| 650 | 0 | 4 |
_aAlzheimer Disease _xdrug therapy |
| 650 | 0 | 4 |
_aAnti-Inflammatory Agents, Non-Steroidal _xchemical synthesis |
| 650 | 0 | 4 |
_aCholinesterase Inhibitors _xchemical synthesis |
| 650 | 0 | 4 | _aDonepezil |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 | _aHep G2 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHydrazones _xchemistry |
| 650 | 0 | 4 |
_aIndans _xchemical synthesis |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aNeuroprotective Agents _xchemical synthesis |
| 650 | 0 | 4 |
_aPiperidines _xchemical synthesis |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _ade Freitas Silva, Matheus | |
| 700 | 1 | _aDivino da Rocha, Miguel | |
| 700 | 1 | _aCastelli, Maísa Rosa | |
| 700 | 1 | _aRiquiel, Mariana Máximo | |
| 700 | 1 | _aMachado, Rafael Pereira | |
| 700 | 1 | _aVaz, Sarah Macedo | |
| 700 | 1 | _aSimões de Lima, Laís Medeiros | |
| 700 | 1 | _aMancini, Karla Cristine | |
| 700 | 1 | _aMarques de Oliveira, Patrícia Cruz | |
| 700 | 1 | _aMorais, Élida Parreira | |
| 700 | 1 | _aGontijo, Vanessa Silva | |
| 700 | 1 | _ada Silva, Fernanda Motta R | |
| 700 | 1 | _aD'Alincourt da Fonseca Peçanha, Dora | |
| 700 | 1 | _aCastro, Newton Gonçalves | |
| 700 | 1 | _aNeves, Gilda A | |
| 700 | 1 | _aGiusti-Paiva, Alexandre | |
| 700 | 1 | _aVilela, Fabiana Cardoso | |
| 700 | 1 | _aOrlandi, Lidiane | |
| 700 | 1 | _aCamps, Ihosvany | |
| 700 | 1 | _aVeloso, Márcia Paranho | |
| 700 | 1 | _aLeomil Coelho, Luis Felipe | |
| 700 | 1 | _aIonta, Marisa | |
| 700 | 1 | _aFerreira-Silva, Guilherme Álvaro | |
| 700 | 1 | _aPereira, Rodrigo Machado | |
| 700 | 1 | _aDardenne, Laurent E | |
| 700 | 1 | _aGuedes, Isabella Alvim | |
| 700 | 1 | _ade Oliveira Carneiro Junior, Wellerson | |
| 700 | 1 | _aQuaglio Bellozi, Paula Maria | |
| 700 | 1 | _aPinheiro de Oliveira, Antônio Carlos | |
| 700 | 1 | _aFerreira, Fábio Furlan | |
| 700 | 1 | _aPruccoli, Letizia | |
| 700 | 1 | _aTarozzi, Andrea | |
| 700 | 1 | _aViegas, Claudio | |
| 773 | 0 |
_tEuropean journal of medicinal chemistry _gvol. 147 _gp. 48-65 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.ejmech.2018.01.066 _zAvailable from publisher's website |
| 999 |
_c28064487 _d28064487 |
||