000 01695 a2200445 4500
005 20250517200356.0
264 0 _c20190228
008 201902s 0 0 eng d
022 _a1432-0851
024 7 _a10.1007/s00262-018-2120-5
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aScheffel, Matthew J
245 0 0 _aN-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner.
_h[electronic resource]
260 _bCancer immunology, immunotherapy : CII
_cApr 2018
300 _a691-702 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAcetylcysteine
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aCells, Cultured
650 0 4 _aForkhead Box Protein O1
_xmetabolism
650 0 4 _aFree Radical Scavengers
_xpharmacology
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImmunotherapy, Adoptive
650 0 4 _aLymphocyte Activation
650 0 4 _aMelanoma
_xdrug therapy
650 0 4 _aMice
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aSignal Transduction
650 0 4 _aT-Lymphocytes, Cytotoxic
_ximmunology
700 1 _aScurti, Gina
700 1 _aWyatt, Megan M
700 1 _aGarrett-Mayer, Elizabeth
700 1 _aPaulos, Chrystal M
700 1 _aNishimura, Michael I
700 1 _aVoelkel-Johnson, Christina
773 0 _tCancer immunology, immunotherapy : CII
_gvol. 67
_gno. 4
_gp. 691-702
856 4 0 _uhttps://doi.org/10.1007/s00262-018-2120-5
_zAvailable from publisher's website
999 _c28040313
_d28040313