000 01657 a2200445 4500
005 20250517200349.0
264 0 _c20180322
008 201803s 0 0 eng d
022 _a1768-3254
024 7 _a10.1016/j.ejmech.2018.01.021
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAboeldahab, Alshimaa M A
245 0 0 _aSpirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cFeb 2018
300 _a79-92 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Design
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aHep G2 Cells
650 0 4 _aHistone Deacetylase Inhibitors
_xchemical synthesis
650 0 4 _aHistone Deacetylases
_xmetabolism
650 0 4 _aHumans
650 0 4 _aMCF-7 Cells
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aPolymerization
_xdrug effects
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTriazoles
_xchemical synthesis
650 0 4 _aTubulin
_xmetabolism
700 1 _aBeshr, Eman A M
700 1 _aShoman, Mai E
700 1 _aRabea, Safwat M
700 1 _aAly, Omar M
773 0 _tEuropean journal of medicinal chemistry
_gvol. 146
_gp. 79-92
856 4 0 _uhttps://doi.org/10.1016/j.ejmech.2018.01.021
_zAvailable from publisher's website
999 _c28039968
_d28039968