000			02044 a2200505 4500
005			20250517195211.0
264		0	_c20190617
008			201906s 0 0 eng d
022			_a2041-4889
024	7		_a10.1038/s41419-017-0075-7 _2doi
040			_aNLM _beng _cNLM
100	1		_aJin, Bei
245	0	0	_aAnthelmintic niclosamide suppresses transcription of BCR-ABL fusion oncogene via disabling Sp1 and induces apoptosis in imatinib-resistant CML cells harboring T315I mutant. _h[electronic resource]
260			_bCell death & disease _c01 2018
300			_a68 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAnthelmintics _xpharmacology
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDown-Regulation _xdrug effects
650	0	4	_aDrug Resistance, Neoplasm _xdrug effects
650	0	4	_aFusion Proteins, bcr-abl _xgenetics
650	0	4	_aImatinib Mesylate _xpharmacology
650	0	4	_aLeukemia, Myelogenous, Chronic, BCR-ABL Positive _xgenetics
650	0	4	_aMice, Nude
650	0	4	_aMitochondria _xdrug effects
650	0	4	_aMitogen-Activated Protein Kinase Kinases _xantagonists & inhibitors
650	0	4	_aModels, Biological
650	0	4	_aMutation _xgenetics
650	0	4	_aMyeloid Cell Leukemia Sequence 1 Protein _xmetabolism
650	0	4	_aNiclosamide _xpharmacology
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aSp1 Transcription Factor _xmetabolism
650	0	4	_aSurvival Analysis
650	0	4	_aTranscription, Genetic _xdrug effects
650	0	4	_aX-Linked Inhibitor of Apoptosis Protein _xmetabolism
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aWang, Chengyan
700	1		_aShen, Yingying
700	1		_aPan, Jingxuan
773	0		_tCell death & disease _gvol. 9 _gno. 2 _gp. 68
856	4	0	_uhttps://doi.org/10.1038/s41419-017-0075-7 _zAvailable from publisher's website
999			_c28004009 _d28004009