000 01669 a2200433 4500
005 20250517193632.0
264 0 _c20180215
008 201802s 0 0 eng d
022 _a1090-2104
024 7 _a10.1016/j.bbrc.2018.01.009
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aQu, Bo
245 0 0 _aMiR-449 overexpression inhibits osteogenic differentiation of bone marrow mesenchymal stem cells via suppressing Sirt1/Fra-1 pathway in high glucose and free fatty acids microenvironment.
_h[electronic resource]
260 _bBiochemical and biophysical research communications
_c01 2018
300 _a120-126 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aCell Differentiation
_xphysiology
650 0 4 _aCells, Cultured
650 0 4 _aFatty Acids, Nonesterified
_xmetabolism
650 0 4 _aGlucose
_xmetabolism
650 0 4 _aHumans
650 0 4 _aMesenchymal Stem Cells
_xcytology
650 0 4 _aOsteoblasts
_xcytology
650 0 4 _aOsteogenesis
_xphysiology
650 0 4 _aProto-Oncogene Proteins c-fos
_xmetabolism
650 0 4 _aSignal Transduction
_xphysiology
650 0 4 _aSirtuin 1
_xmetabolism
650 0 4 _aStem Cell Niche
_xphysiology
650 0 4 _aUp-Regulation
_xphysiology
700 1 _aGong, Kai
700 1 _aYang, Hong-Sheng
700 1 _aLi, Yu-Gang
700 1 _aJiang, Tao
700 1 _aZeng, Zhi-Mou
700 1 _aCao, Zong-Rui
700 1 _aPan, Xian-Ming
773 0 _tBiochemical and biophysical research communications
_gvol. 496
_gno. 1
_gp. 120-126
856 4 0 _uhttps://doi.org/10.1016/j.bbrc.2018.01.009
_zAvailable from publisher's website
999 _c27952618
_d27952618