000 01555 a2200409 4500
005 20250517193125.0
264 0 _c20190408
008 201904s 0 0 eng d
022 _a1520-6017
024 7 _a10.1016/j.xphs.2017.12.024
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPurohit, Hitesh S
245 0 0 _aInvestigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation.
_h[electronic resource]
260 _bJournal of pharmaceutical sciences
_c05 2018
300 _a1330-1341 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aCapsules
650 0 4 _aComputer Simulation
650 0 4 _aCrystallization
650 0 4 _aHumans
650 0 4 _aImmunosuppressive Agents
_xadministration & dosage
650 0 4 _aModels, Biological
650 0 4 _aPowder Diffraction
650 0 4 _aSolubility
650 0 4 _aTacrolimus
_xadministration & dosage
650 0 4 _aTherapeutic Equivalency
650 0 4 _aX-Ray Diffraction
700 1 _aTrasi, Niraj S
700 1 _aSun, Dajun D
700 1 _aChow, Edwin C Y
700 1 _aWen, Hong
700 1 _aZhang, Xinyuan
700 1 _aGao, Yi
700 1 _aTaylor, Lynne S
773 0 _tJournal of pharmaceutical sciences
_gvol. 107
_gno. 5
_gp. 1330-1341
856 4 0 _uhttps://doi.org/10.1016/j.xphs.2017.12.024
_zAvailable from publisher's website
999 _c27936778
_d27936778