000 | 01924 a2200577 4500 | ||
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005 | 20250517193055.0 | ||
264 | 0 | _c20180907 | |
008 | 201809s 0 0 eng d | ||
022 | _a1464-3391 | ||
024 | 7 |
_a10.1016/j.bmc.2017.12.015 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aClarke, Earl | |
245 | 0 | 0 |
_aDesign and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry _c02 2018 |
||
300 |
_a798-814 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAdministration, Oral |
650 | 0 | 4 |
_aAminobenzoates _xchemistry |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aBenzoates _xchemistry |
650 | 0 | 4 | _aCOS Cells |
650 | 0 | 4 |
_aCell Survival _xdrug effects |
650 | 0 | 4 | _aChlorocebus aethiops |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 | _aHalf-Life |
650 | 0 | 4 | _aHep G2 Cells |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
650 | 0 | 4 | _aRats |
650 | 0 | 4 |
_aReceptors, Retinoic Acid _xagonists |
650 | 0 | 4 |
_aRetinoic Acid Receptor alpha _xagonists |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTetrahydronaphthalenes _xchemistry |
650 | 0 | 4 | _aRetinoic Acid Receptor gamma |
700 | 1 | _aJarvis, Christopher I | |
700 | 1 | _aGoncalves, Maria B | |
700 | 1 | _aKalindjian, S Barret | |
700 | 1 | _aAdams, David R | |
700 | 1 | _aBrown, Jane T | |
700 | 1 | _aShiers, Jason J | |
700 | 1 | _aTaddei, David M A | |
700 | 1 | _aRavier, Elodie | |
700 | 1 | _aBarlow, Stephanie | |
700 | 1 | _aMiller, Iain | |
700 | 1 | _aSmith, Vanessa | |
700 | 1 | _aBorthwick, Alan D | |
700 | 1 | _aCorcoran, Jonathan P T | |
773 | 0 |
_tBioorganic & medicinal chemistry _gvol. 26 _gno. 4 _gp. 798-814 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmc.2017.12.015 _zAvailable from publisher's website |
999 |
_c27935188 _d27935188 |