000 | 02176 a2200637 4500 | ||
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005 | 20250517191502.0 | ||
264 | 0 | _c20190218 | |
008 | 201902s 0 0 eng d | ||
022 | _a1520-4804 | ||
024 | 7 |
_a10.1021/acs.jmedchem.7b01411 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aHamdouchi, Chafiq | |
245 | 0 | 0 |
_aDiscovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _c02 2018 |
||
300 |
_a934-945 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAdministration, Oral |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aDiabetes Mellitus, Type 2 _xdrug therapy |
650 | 0 | 4 | _aDogs |
650 | 0 | 4 | _aDrug Discovery |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aHypoglycemic Agents _xadministration & dosage |
650 | 0 | 4 | _aMale |
650 | 0 | 4 |
_aPyridines _xadministration & dosage |
650 | 0 | 4 | _aRats |
650 | 0 | 4 |
_aReceptors, G-Protein-Coupled _xagonists |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTriazoles _xadministration & dosage |
700 | 1 | _aMaiti, Pranab | |
700 | 1 | _aWarshawsky, Alan M | |
700 | 1 | _aDeBaillie, Amy C | |
700 | 1 | _aOtto, Keith A | |
700 | 1 | _aWilbur, Kelly L | |
700 | 1 | _aKahl, Steven D | |
700 | 1 | _aPatel Lewis, Anjana | |
700 | 1 | _aCardona, Guemalli R | |
700 | 1 | _aZink, Richard W | |
700 | 1 | _aChen, Keyue | |
700 | 1 | _aCr, Siddaramaiah | |
700 | 1 | _aLineswala, Jayana P | |
700 | 1 | _aNeathery, Grace L | |
700 | 1 | _aBouaichi, Cecilia | |
700 | 1 | _aDiseroad, Benjamin A | |
700 | 1 | _aCampbell, Alison N | |
700 | 1 | _aSweetana, Stephanie A | |
700 | 1 | _aAdams, Lisa A | |
700 | 1 | _aCabrera, Over | |
700 | 1 | _aMa, Xiaosu | |
700 | 1 | _aYumibe, Nathan P | |
700 | 1 | _aMontrose-Rafizadeh, Chahrzad | |
700 | 1 | _aChen, Yanyun | |
700 | 1 | _aMiller, Anne Reifel | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 61 _gno. 3 _gp. 934-945 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.7b01411 _zAvailable from publisher's website |
999 |
_c27884964 _d27884964 |