000 02176 a2200637 4500
005 20250517191502.0
264 0 _c20190218
008 201902s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/acs.jmedchem.7b01411
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHamdouchi, Chafiq
245 0 0 _aDiscovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_c02 2018
300 _a934-945 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aDiabetes Mellitus, Type 2
_xdrug therapy
650 0 4 _aDogs
650 0 4 _aDrug Discovery
650 0 4 _aHumans
650 0 4 _aHypoglycemic Agents
_xadministration & dosage
650 0 4 _aMale
650 0 4 _aPyridines
_xadministration & dosage
650 0 4 _aRats
650 0 4 _aReceptors, G-Protein-Coupled
_xagonists
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTriazoles
_xadministration & dosage
700 1 _aMaiti, Pranab
700 1 _aWarshawsky, Alan M
700 1 _aDeBaillie, Amy C
700 1 _aOtto, Keith A
700 1 _aWilbur, Kelly L
700 1 _aKahl, Steven D
700 1 _aPatel Lewis, Anjana
700 1 _aCardona, Guemalli R
700 1 _aZink, Richard W
700 1 _aChen, Keyue
700 1 _aCr, Siddaramaiah
700 1 _aLineswala, Jayana P
700 1 _aNeathery, Grace L
700 1 _aBouaichi, Cecilia
700 1 _aDiseroad, Benjamin A
700 1 _aCampbell, Alison N
700 1 _aSweetana, Stephanie A
700 1 _aAdams, Lisa A
700 1 _aCabrera, Over
700 1 _aMa, Xiaosu
700 1 _aYumibe, Nathan P
700 1 _aMontrose-Rafizadeh, Chahrzad
700 1 _aChen, Yanyun
700 1 _aMiller, Anne Reifel
773 0 _tJournal of medicinal chemistry
_gvol. 61
_gno. 3
_gp. 934-945
856 4 0 _uhttps://doi.org/10.1021/acs.jmedchem.7b01411
_zAvailable from publisher's website
999 _c27884964
_d27884964