| 000 | 01898 a2200541 4500 | ||
|---|---|---|---|
| 005 | 20250517191304.0 | ||
| 264 | 0 | _c20180709 | |
| 008 | 201807s 0 0 eng d | ||
| 022 | _a1091-6490 | ||
| 024 | 7 |
_a10.1073/pnas.1711243115 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHandley, Renee R | |
| 245 | 0 | 0 |
_aBrain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _c12 2017 |
||
| 300 |
_aE11293-E11302 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aAnimals, Genetically Modified |
| 650 | 0 | 4 |
_aCorpus Striatum _xmetabolism |
| 650 | 0 | 4 | _aDisease Models, Animal |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHuntingtin Protein _xgenetics |
| 650 | 0 | 4 |
_aHuntington Disease _xgenetics |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aSheep |
| 650 | 0 | 4 |
_aTrinucleotide Repeat Expansion _xgenetics |
| 650 | 0 | 4 |
_aUrea _xmetabolism |
| 700 | 1 | _aReid, Suzanne J | |
| 700 | 1 | _aBrauning, Rudiger | |
| 700 | 1 | _aMaclean, Paul | |
| 700 | 1 | _aMears, Emily R | |
| 700 | 1 | _aFourie, Imche | |
| 700 | 1 | _aPatassini, Stefano | |
| 700 | 1 | _aCooper, Garth J S | |
| 700 | 1 | _aRudiger, Skye R | |
| 700 | 1 | _aMcLaughlan, Clive J | |
| 700 | 1 | _aVerma, Paul J | |
| 700 | 1 | _aGusella, James F | |
| 700 | 1 | _aMacDonald, Marcy E | |
| 700 | 1 | _aWaldvogel, Henry J | |
| 700 | 1 | _aBawden, C Simon | |
| 700 | 1 | _aFaull, Richard L M | |
| 700 | 1 | _aSnell, Russell G | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 114 _gno. 52 _gp. E11293-E11302 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.1711243115 _zAvailable from publisher's website |
| 999 |
_c27878475 _d27878475 |
||