000 02148 a2200697 4500
005 20250517190924.0
264 0 _c20180418
008 201804s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.aao4426
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLodato, Michael A
245 0 0 _aAging and neurodegeneration are associated with increased mutations in single human neurons.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_c02 2018
300 _a555-559 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAge Factors
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAging
_xgenetics
650 0 4 _aChild
650 0 4 _aChild, Preschool
650 0 4 _aCockayne Syndrome
_xgenetics
650 0 4 _aDNA Mutational Analysis
650 0 4 _aDNA Repair
_xgenetics
650 0 4 _aFemale
650 0 4 _aHippocampus
_xcytology
650 0 4 _aHumans
650 0 4 _aInfant
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMutation Rate
650 0 4 _aNeurodegenerative Diseases
_xgenetics
650 0 4 _aNeurogenesis
_xgenetics
650 0 4 _aNeurons
650 0 4 _aPrefrontal Cortex
_xcytology
650 0 4 _aSingle-Cell Analysis
650 0 4 _aWhole Genome Sequencing
650 0 4 _aXeroderma Pigmentosum
_xgenetics
650 0 4 _aYoung Adult
700 1 _aRodin, Rachel E
700 1 _aBohrson, Craig L
700 1 _aCoulter, Michael E
700 1 _aBarton, Alison R
700 1 _aKwon, Minseok
700 1 _aSherman, Maxwell A
700 1 _aVitzthum, Carl M
700 1 _aLuquette, Lovelace J
700 1 _aYandava, Chandri N
700 1 _aYang, Pengwei
700 1 _aChittenden, Thomas W
700 1 _aHatem, Nicole E
700 1 _aRyu, Steven C
700 1 _aWoodworth, Mollie B
700 1 _aPark, Peter J
700 1 _aWalsh, Christopher A
773 0 _tScience (New York, N.Y.)
_gvol. 359
_gno. 6375
_gp. 555-559
856 4 0 _uhttps://doi.org/10.1126/science.aao4426
_zAvailable from publisher's website
999 _c27866463
_d27866463