000 | 01672 a2200457 4500 | ||
---|---|---|---|
005 | 20250517190842.0 | ||
264 | 0 | _c20190415 | |
008 | 201904s 0 0 eng d | ||
022 | _a1520-4804 | ||
024 | 7 |
_a10.1021/acs.jmedchem.7b00738 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aNeelarapu, Raghupathi | |
245 | 0 | 0 |
_aDesign and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _c02 2018 |
||
300 |
_a1450-1473 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntimalarials _xchemical synthesis |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aPiperazine _xchemistry |
650 | 0 | 4 |
_aPlasmodium falciparum _xdrug effects |
650 | 0 | 4 |
_aQuinolones _xchemistry |
650 | 0 | 4 | _aSolubility |
650 | 0 | 4 | _aStructure-Activity Relationship |
700 | 1 | _aMaignan, Jordany R | |
700 | 1 | _aLichorowic, Cynthia L | |
700 | 1 | _aMonastyrskyi, Andrii | |
700 | 1 | _aMutka, Tina S | |
700 | 1 | _aLaCrue, Alexis N | |
700 | 1 | _aBlake, Lynn D | |
700 | 1 | _aCasandra, Debora | |
700 | 1 | _aMashkouri, Sherwin | |
700 | 1 | _aBurrows, Jeremy N | |
700 | 1 | _aWillis, Paul A | |
700 | 1 | _aKyle, Dennis E | |
700 | 1 | _aManetsch, Roman | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 61 _gno. 4 _gp. 1450-1473 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.7b00738 _zAvailable from publisher's website |
999 |
_c27864216 _d27864216 |