000 01919 a2200565 4500
005 20250517190639.0
264 0 _c20181217
008 201812s 0 0 eng d
022 _a1873-2968
024 7 _a10.1016/j.bcp.2017.11.022
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSu, Yongwei
245 0 0 _aTargeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo.
_h[electronic resource]
260 _bBiochemical pharmacology
_c02 2018
300 _a13-26 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aChild
650 0 4 _aChild, Preschool
650 0 4 _aDrug Delivery Systems
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xgenetics
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aHumans
650 0 4 _aLeukemia, Myeloid, Acute
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMetabolic Networks and Pathways
_xdrug effects
650 0 4 _aMiddle Aged
650 0 4 _aPhosphatidylinositol 3-Kinases
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xgenetics
650 0 4 _aTOR Serine-Threonine Kinases
_xgenetics
650 0 4 _aUp-Regulation
650 0 4 _aYoung Adult
700 1 _aLi, Xinyu
700 1 _aMa, Jun
700 1 _aZhao, Jianyun
700 1 _aLiu, Shuang
700 1 _aWang, Guan
700 1 _aEdwards, Holly
700 1 _aTaub, Jeffrey W
700 1 _aLin, Hai
700 1 _aGe, Yubin
773 0 _tBiochemical pharmacology
_gvol. 148
_gp. 13-26
856 4 0 _uhttps://doi.org/10.1016/j.bcp.2017.11.022
_zAvailable from publisher's website
999 _c27857460
_d27857460