| 000 | 01921 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250517185947.0 | ||
| 264 | 0 | _c20190401 | |
| 008 | 201904s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/acs.jmedchem.7b01562 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aTaban, Ismail M | |
| 245 | 0 | 0 |
_aNovel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _c12 2017 |
||
| 300 |
_a10257-10267 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAntitubercular Agents _xchemistry |
| 650 | 0 | 4 |
_aBacterial Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 | _aCrystallography, X-Ray |
| 650 | 0 | 4 |
_aCytochrome P-450 Enzyme Inhibitors _xchemical synthesis |
| 650 | 0 | 4 |
_aCytochrome P-450 Enzyme System _xchemistry |
| 650 | 0 | 4 |
_aDrug Evaluation, Preclinical _xmethods |
| 650 | 0 | 4 | _aMicrobial Sensitivity Tests |
| 650 | 0 | 4 | _aMolecular Docking Simulation |
| 650 | 0 | 4 |
_aMycobacterium tuberculosis _xdrug effects |
| 650 | 0 | 4 |
_aPyrazoles _xchemistry |
| 650 | 0 | 4 |
_aSmall Molecule Libraries _xchemistry |
| 650 | 0 | 4 | _aSpectrophotometry, Ultraviolet |
| 700 | 1 | _aElshihawy, Hosam E A E | |
| 700 | 1 | _aTorun, Beyza | |
| 700 | 1 | _aZucchini, Benedetta | |
| 700 | 1 | _aWilliamson, Clare J | |
| 700 | 1 | _aAltuwairigi, Dania | |
| 700 | 1 | _aNgu, Adeline S T | |
| 700 | 1 | _aMcLean, Kirsty J | |
| 700 | 1 | _aLevy, Colin W | |
| 700 | 1 | _aSood, Sakshi | |
| 700 | 1 | _aMarino, Leonardo B | |
| 700 | 1 | _aMunro, Andrew W | |
| 700 | 1 | _ade Carvalho, Luiz Pedro S | |
| 700 | 1 | _aSimons, Claire | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 60 _gno. 24 _gp. 10257-10267 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.7b01562 _zAvailable from publisher's website |
| 999 |
_c27835281 _d27835281 |
||