| 000 | 01550 a2200469 4500 | ||
|---|---|---|---|
| 005 | 20250517185405.0 | ||
| 264 | 0 | _c20190703 | |
| 008 | 201907s 0 0 eng d | ||
| 022 | _a2045-2322 | ||
| 024 | 7 |
_a10.1038/s41598-017-16405-2 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aDzyurkevich, Mikhail S | |
| 245 | 0 | 0 |
_aPyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. _h[electronic resource] |
| 260 |
_bScientific reports _c11 2017 |
||
| 300 |
_a16072 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAllosteric Site |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aDiabetes Mellitus, Type 2 _xdrug therapy |
| 650 | 0 | 4 |
_aEnzyme Activators _xchemical synthesis |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aGlucokinase _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMolecular Docking Simulation |
| 650 | 0 | 4 |
_aPyridoxine _xchemical synthesis |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aToxicity Tests, Acute |
| 700 | 1 | _aBabkov, Denis A | |
| 700 | 1 | _aShtyrlin, Nikita V | |
| 700 | 1 | _aMayka, Olga Yu | |
| 700 | 1 | _aIksanova, Alfiya G | |
| 700 | 1 | _aVassiliev, Pavel M | |
| 700 | 1 | _aBalakin, Konstantin V | |
| 700 | 1 | _aSpasov, Alexander A | |
| 700 | 1 | _aTarasov, Vadim V | |
| 700 | 1 | _aBarreto, George | |
| 700 | 1 | _aShtyrlin, Yurii G | |
| 700 | 1 | _aAliev, Gjumrakch | |
| 773 | 0 |
_tScientific reports _gvol. 7 _gno. 1 _gp. 16072 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/s41598-017-16405-2 _zAvailable from publisher's website |
| 999 |
_c27817466 _d27817466 |
||