000 01518 a2200397 4500
005 20250517185042.0
264 0 _c20181001
008 201810s 0 0 eng d
022 _a1742-7843
024 7 _a10.1111/bcpt.12933
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMurray, Michael
245 0 0 _aVariation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors.
_h[electronic resource]
260 _bBasic & clinical pharmacology & toxicology
_cApr 2018
300 _a388-395 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntipsychotic Agents
_xmetabolism
650 0 4 _aBiotransformation
650 0 4 _aClozapine
_xanalogs & derivatives
650 0 4 _aCytochrome P-450 CYP1A2
_xmetabolism
650 0 4 _aCytochrome P-450 CYP1A2 Inhibitors
_xpharmacology
650 0 4 _aCytochrome P-450 CYP3A
_xmetabolism
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
_xpharmacology
650 0 4 _aDrug Interactions
650 0 4 _aFluvoxamine
_xpharmacology
650 0 4 _aHumans
650 0 4 _aHydroxylation
650 0 4 _aKetoconazole
_xpharmacology
650 0 4 _aLiver
_xcytology
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aOxidation-Reduction
700 1 _aZhang, Wei V
700 1 _aEdwards, Robert J
773 0 _tBasic & clinical pharmacology & toxicology
_gvol. 122
_gno. 4
_gp. 388-395
856 4 0 _uhttps://doi.org/10.1111/bcpt.12933
_zAvailable from publisher's website
999 _c27805552
_d27805552