000 01787 a2200529 4500
005 20250517183259.0
264 0 _c20190715
008 201907s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/s41598-017-14960-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSun, Li
245 0 0 _aMetoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria.
_h[electronic resource]
260 _bScientific reports
_c11 2017
300 _a14941 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAMP-Activated Protein Kinase Kinases
650 0 4 _aAdrenergic beta-1 Receptor Antagonists
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAtrial Fibrillation
_xetiology
650 0 4 _aAtrial Remodeling
_xdrug effects
650 0 4 _aCell Line
650 0 4 _aChronic Disease
650 0 4 _aDisease Models, Animal
650 0 4 _aDogs
650 0 4 _aHeart Atria
_xdrug effects
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMetoprolol
_xpharmacology
650 0 4 _aProtein Kinases
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSirtuin 1
_xmetabolism
650 0 4 _aSleep Apnea, Obstructive
_xcomplications
700 1 _aYan, Sen
700 1 _aWang, Xiaoyu
700 1 _aZhao, Shiqi
700 1 _aLi, Hui
700 1 _aWang, Yike
700 1 _aLu, Shuang
700 1 _aDong, Xinwen
700 1 _aZhao, Jing
700 1 _aYu, Shengzhu
700 1 _aLi, Minghui
700 1 _aLi, Yue
773 0 _tScientific reports
_gvol. 7
_gno. 1
_gp. 14941
856 4 0 _uhttps://doi.org/10.1038/s41598-017-14960-2
_zAvailable from publisher's website
999 _c27748844
_d27748844