000 01484 a2200385 4500
005 20250517182119.0
264 0 _c20171113
008 201711s 0 0 eng d
022 _a1460-2105
024 7 _a10.1093/jnci/djx071
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aStacpoole, Peter W
245 0 0 _aTherapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
_h[electronic resource]
260 _bJournal of the National Cancer Institute
_c11 2017
500 _aPublication Type: Journal Article; Review
650 0 4 _aAcetyl Coenzyme A
_xmetabolism
650 0 4 _aAdenosine Triphosphate
_xbiosynthesis
650 0 4 _aBiomimetics
650 0 4 _aCitric Acid Cycle
_xphysiology
650 0 4 _aDichloroacetic Acid
_xpharmacology
650 0 4 _aEnergy Metabolism
650 0 4 _aGlycolysis
650 0 4 _aHumans
650 0 4 _aIsoenzymes
_xmetabolism
650 0 4 _aMitochondria
_xmetabolism
650 0 4 _aNAD
_xmetabolism
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aOxidative Phosphorylation
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aPyruvate Dehydrogenase Acetyl-Transferring Kinase
650 0 4 _aPyruvate Dehydrogenase Complex
_xantagonists & inhibitors
650 0 4 _aPyruvic Acid
_xmetabolism
773 0 _tJournal of the National Cancer Institute
_gvol. 109
_gno. 11
856 4 0 _uhttps://doi.org/10.1093/jnci/djx071
_zAvailable from publisher's website
999 _c27711739
_d27711739