000 02527 a2200697 4500
005 20250517181824.0
264 0 _c20180611
008 201806s 0 0 eng d
022 _a2047-9980
024 7 _a10.1161/JAHA.117.006635
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aStuhlmiller, Timothy J
245 0 0 _aKinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Receptor Inhibition.
_h[electronic resource]
260 _bJournal of the American Heart Association
_cOct 2017
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xtoxicity
650 0 4 _aCardiotoxicity
650 0 4 _aCells, Cultured
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEchocardiography
650 0 4 _aErbB Receptors
_xantagonists & inhibitors
650 0 4 _aErlotinib Hydrochloride
_xtoxicity
650 0 4 _aFatty Acids
_xmetabolism
650 0 4 _aFemale
650 0 4 _aGene Expression Profiling
650 0 4 _aHeart
_xdiagnostic imaging
650 0 4 _aHeart Diseases
_xchemically induced
650 0 4 _aIndoles
_xtoxicity
650 0 4 _aMice
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aMyocardial Contraction
_xdrug effects
650 0 4 _aMyocardium
_xenzymology
650 0 4 _aMyocytes, Cardiac
_xdrug effects
650 0 4 _aNiacinamide
_xanalogs & derivatives
650 0 4 _aOxidation-Reduction
650 0 4 _aPhenylurea Compounds
_xtoxicity
650 0 4 _aProtein Interaction Maps
650 0 4 _aProtein Kinase Inhibitors
_xtoxicity
650 0 4 _aProteomics
650 0 4 _aPyrroles
_xtoxicity
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aSTAT3 Transcription Factor
_xantagonists & inhibitors
650 0 4 _aSignal Transduction
650 0 4 _aSorafenib
650 0 4 _aSunitinib
650 0 4 _aTime Factors
700 1 _aZawistowski, Jon S
700 1 _aChen, Xin
700 1 _aSciaky, Noah
700 1 _aAngus, Steven P
700 1 _aHicks, Sean T
700 1 _aParry, Traci L
700 1 _aHuang, Wei
700 1 _aBeak, Ju Youn
700 1 _aWillis, Monte S
700 1 _aJohnson, Gary L
700 1 _aJensen, Brian C
773 0 _tJournal of the American Heart Association
_gvol. 6
_gno. 10
856 4 0 _uhttps://doi.org/10.1161/JAHA.117.006635
_zAvailable from publisher's website
999 _c27703617
_d27703617