000 | 01688 a2200457 4500 | ||
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005 | 20250517181816.0 | ||
264 | 0 | _c20171121 | |
008 | 201711s 0 0 eng d | ||
022 | _a1464-3405 | ||
024 | 7 |
_a10.1016/j.bmcl.2017.10.009 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aCook, James | |
245 | 0 | 0 |
_aDesign and synthesis of a novel series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _c11 2017 |
||
300 |
_a5002-5005 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 |
_aBridged Bicyclo Compounds _xchemical synthesis |
650 | 0 | 4 | _aCrystallography, X-Ray |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aHydrogen Bonding |
650 | 0 | 4 | _aMolecular Conformation |
650 | 0 | 4 |
_aNicotinic Agonists _xchemistry |
650 | 0 | 4 |
_aOctanes _xchemical synthesis |
650 | 0 | 4 | _aProtein Binding |
650 | 0 | 4 |
_aReceptors, Serotonin, 5-HT3 _xchemistry |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 |
_aalpha7 Nicotinic Acetylcholine Receptor _xchemistry |
700 | 1 | _aZusi, F Christopher | |
700 | 1 | _aHill, Matthew D | |
700 | 1 | _aFang, Haiquan | |
700 | 1 | _aPearce, Bradley | |
700 | 1 | _aPark, Hyunsoo | |
700 | 1 | _aGallagher, Lizbeth | |
700 | 1 | _aMcDonald, Ivar M | |
700 | 1 | _aBristow, Linda | |
700 | 1 | _aMacor, John E | |
700 | 1 | _aOlson, Richard E | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 27 _gno. 22 _gp. 5002-5005 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2017.10.009 _zAvailable from publisher's website |
999 |
_c27703189 _d27703189 |