000 01640 a2200481 4500
005 20250517181436.0
264 0 _c20171205
008 201712s 0 0 eng d
022 _a1872-7980
024 7 _a10.1016/j.canlet.2017.10.006
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhuge, Weishan
245 0 0 _aCostunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer.
_h[electronic resource]
260 _bCancer letters
_c01 2018
300 _a46-58 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aActivating Transcription Factor 4
_xphysiology
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents, Phytogenic
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aColonic Neoplasms
_xdrug therapy
650 0 4 _aEndoplasmic Reticulum Stress
650 0 4 _aFemale
650 0 4 _aHCT116 Cells
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aSesquiterpenes
_xmetabolism
650 0 4 _aThioredoxin Reductase 1
_xantagonists & inhibitors
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aChen, Ruijie
700 1 _aVladimir, Katanaev
700 1 _aDong, Xidan
700 1 _aZia, Khan
700 1 _aSun, Xiangwei
700 1 _aDai, Xuanxuan
700 1 _aBao, Miao
700 1 _aShen, Xian
700 1 _aLiang, Guang
773 0 _tCancer letters
_gvol. 412
_gp. 46-58
856 4 0 _uhttps://doi.org/10.1016/j.canlet.2017.10.006
_zAvailable from publisher's website
999 _c27690536
_d27690536