000 | 02262 a2200733 4500 | ||
---|---|---|---|
005 | 20250517181212.0 | ||
264 | 0 | _c20171206 | |
008 | 201712s 0 0 eng d | ||
022 | _a1464-3405 | ||
024 | 7 |
_a10.1016/j.bmcl.2017.09.056 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aStorer, R Ian | |
245 | 0 | 0 |
_aHighly potent and selective Na _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _c11 2017 |
||
300 |
_a4805-4811 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 | _aDogs |
650 | 0 | 4 | _aHalf-Life |
650 | 0 | 4 |
_aHepatocytes _xmetabolism |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aInfusions, Intravenous |
650 | 0 | 4 | _aInhibitory Concentration 50 |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 |
_aNAV1.7 Voltage-Gated Sodium Channel _xchemistry |
650 | 0 | 4 |
_aPain _xdrug therapy |
650 | 0 | 4 |
_aPiperidines _xchemistry |
650 | 0 | 4 | _aProtein Binding |
650 | 0 | 4 | _aProtein Structure, Tertiary |
650 | 0 | 4 |
_aPyridines _xchemistry |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aSulfonamides _xchemistry |
650 | 0 | 4 | _aThiadiazoles |
650 | 0 | 4 |
_aVoltage-Gated Sodium Channel Blockers _xchemistry |
700 | 1 | _aPike, Andy | |
700 | 1 | _aSwain, Nigel A | |
700 | 1 | _aAlexandrou, Aristos J | |
700 | 1 | _aBechle, Bruce M | |
700 | 1 | _aBlakemore, David C | |
700 | 1 | _aBrown, Alan D | |
700 | 1 | _aCastle, Neil A | |
700 | 1 | _aCorbett, Matthew S | |
700 | 1 | _aFlanagan, Neil J | |
700 | 1 | _aFengas, David | |
700 | 1 | _aJohnson, M Scott | |
700 | 1 | _aJones, Lyn H | |
700 | 1 | _aMarron, Brian E | |
700 | 1 | _aPayne, C Elizabeth | |
700 | 1 | _aPrintzenhoff, David | |
700 | 1 | _aRawson, David J | |
700 | 1 | _aRose, Colin R | |
700 | 1 | _aRyckmans, Thomas | |
700 | 1 | _aSun, Jianmin | |
700 | 1 | _aTheile, Jonathan W | |
700 | 1 | _aTorella, Rubben | |
700 | 1 | _aTseng, Elaine | |
700 | 1 | _aWarmus, Joseph S | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 27 _gno. 21 _gp. 4805-4811 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2017.09.056 _zAvailable from publisher's website |
999 |
_c27682711 _d27682711 |