000 02087 a2200565 4500
005 20250517175522.0
264 0 _c20180801
008 201808s 0 0 eng d
022 _a1557-3265
024 7 _a10.1158/1078-0432.CCR-17-0676
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLynch, James T
245 0 0 _aInhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors.
_h[electronic resource]
260 _bClinical cancer research : an official journal of the American Association for Cancer Research
_cDec 2017
300 _a7584-7595 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAniline Compounds
_xadministration & dosage
650 0 4 _aAnimals
650 0 4 _aCell Line, Tumor
650 0 4 _aChromones
_xadministration & dosage
650 0 4 _aClass II Phosphatidylinositol 3-Kinases
_xgenetics
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aHumans
650 0 4 _aHydroxymethylglutaryl-CoA Synthase
_xgenetics
650 0 4 _aMetabolic Networks and Pathways
_xgenetics
650 0 4 _aMice
650 0 4 _aPTEN Phosphohydrolase
_xgenetics
650 0 4 _aTriple Negative Breast Neoplasms
_xdrug therapy
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aPolanska, Urszula M
700 1 _aDelpuech, Oona
700 1 _aHancox, Urs
700 1 _aTrinidad, Antonio G
700 1 _aMichopoulos, Filippos
700 1 _aLenaghan, Carol
700 1 _aMcEwen, Robert
700 1 _aBradford, James
700 1 _aPolanski, Radek
700 1 _aEllston, Rebecca
700 1 _aAvivar-Valderas, Alvaro
700 1 _aPilling, James
700 1 _aStaniszewska, Anna
700 1 _aCumberbatch, Marie
700 1 _aCritchlow, Susan E
700 1 _aCruzalegui, Francisco
700 1 _aBarry, Simon T
773 0 _tClinical cancer research : an official journal of the American Association for Cancer Research
_gvol. 23
_gno. 24
_gp. 7584-7595
856 4 0 _uhttps://doi.org/10.1158/1078-0432.CCR-17-0676
_zAvailable from publisher's website
999 _c27625735
_d27625735