000 01636 a2200517 4500
005 20250517175139.0
264 0 _c20180727
008 201807s 0 0 eng d
022 _a2159-3345
024 7 _a10.1089/nat.2017.0683
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGupta, Shashi
245 0 0 _aPharmacokinetic Properties of DNA Aptamers with Base Modifications.
_h[electronic resource]
260 _bNucleic acid therapeutics
_cDec 2017
300 _a345-353 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAptamers, Nucleotide
_xadministration & dosage
650 0 4 _aBase Sequence
650 0 4 _aDrug Design
650 0 4 _aHydrophobic and Hydrophilic Interactions
650 0 4 _aLigands
650 0 4 _aLinear Models
650 0 4 _aMale
650 0 4 _aPolyethylene Glycols
_xchemistry
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aSELEX Aptamer Technique
_xmethods
650 0 4 _aStatistics, Nonparametric
650 0 4 _aUracil
_xchemistry
700 1 _aDrolet, Daniel W
700 1 _aWolk, Steven K
700 1 _aWaugh, Sheela M
700 1 _aRohloff, John C
700 1 _aCarter, Jeffery D
700 1 _aMayfield, Wesley S
700 1 _aOtis, Matthew R
700 1 _aFowler, Catherine R
700 1 _aSuzuki, Tomoki
700 1 _aHirota, Masao
700 1 _aIshikawa, Yuichi
700 1 _aSchneider, Daniel J
700 1 _aJanjic, Nebojsa
773 0 _tNucleic acid therapeutics
_gvol. 27
_gno. 6
_gp. 345-353
856 4 0 _uhttps://doi.org/10.1089/nat.2017.0683
_zAvailable from publisher's website
999 _c27614920
_d27614920