000 01665 a2200481 4500
005 20250517174629.0
264 0 _c20180705
008 201807s 0 0 eng d
022 _a1879-0712
024 7 _a10.1016/j.ejphar.2017.09.031
_2doi
040 _aNLM
_beng
_cNLM
100 1 _avan Diemen, Marcus P J
245 0 0 _aValidation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study.
_h[electronic resource]
260 _bEuropean journal of pharmacology
_cNov 2017
300 _a290-297 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Validation Study
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFemale
650 0 4 _aHand Strength
650 0 4 _aHealthy Volunteers
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aOxygen Consumption
_xdrug effects
650 0 4 _aSafety
650 0 4 _aSimvastatin
_xadverse effects
650 0 4 _aTime Factors
650 0 4 _aUbiquinone
_xanalogs & derivatives
700 1 _aBerends, Cécile L
700 1 _aAkram, Naila
700 1 _aWezel, Joep
700 1 _aTeeuwisse, Wouter M
700 1 _aMik, Bert G
700 1 _aKan, Hermien E
700 1 _aWebb, Andrew
700 1 _aBeenakker, Jan Willem M
700 1 _aGroeneveld, Geert Jan
773 0 _tEuropean journal of pharmacology
_gvol. 815
_gp. 290-297
856 4 0 _uhttps://doi.org/10.1016/j.ejphar.2017.09.031
_zAvailable from publisher's website
999 _c27597355
_d27597355