000			02316 a2200577 4500
005			20250517173531.0
264		0	_c20190506
008			201905s 0 0 eng d
022			_a1747-4949
024	7		_a10.1177/1747493017731947 _2doi
040			_aNLM _beng _cNLM
100	1		_aBlair, Gordon W
245	0	0	_aPreventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination. _h[electronic resource]
260			_bInternational journal of stroke : official journal of the International Stroke Society _c07 2018
300			_a530-538 p. _bdigital
500			_aPublication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650	0	4	_aAge Factors
650	0	4	_aCerebral Small Vessel Diseases _xcomplications
650	0	4	_aCilostazol _xtherapeutic use
650	0	4	_aCognition Disorders _xetiology
650	0	4	_aDementia _xetiology
650	0	4	_aDouble-Blind Method
650	0	4	_aFemale
650	0	4	_aFollow-Up Studies
650	0	4	_aHumans
650	0	4	_aIsosorbide Dinitrate _xanalogs & derivatives
650	0	4	_aMagnetic Resonance Imaging
650	0	4	_aMale
650	0	4	_aNeuropsychological Tests
650	0	4	_aSeverity of Illness Index
650	0	4	_aTreatment Outcome
650	0	4	_aUnited Kingdom
650	0	4	_aVasodilator Agents _xtherapeutic use
700	1		_aAppleton, Jason P
700	1		_aLaw, Zhe Kang
700	1		_aDoubal, Fergus
700	1		_aFlaherty, Katie
700	1		_aDooley, Richard
700	1		_aShuler, Kirsten
700	1		_aRichardson, Carla
700	1		_aHamilton, Iona
700	1		_aShi, Yulu
700	1		_aStringer, Michael
700	1		_aBoyd, Julia
700	1		_aThrippleton, Michael J
700	1		_aSprigg, Nikola
700	1		_aBath, Philip M
700	1		_aWardlaw, Joanna M
773	0		_tInternational journal of stroke : official journal of the International Stroke Society _gvol. 13 _gno. 5 _gp. 530-538
856	4	0	_uhttps://doi.org/10.1177/1747493017731947 _zAvailable from publisher's website
999			_c27561004 _d27561004