000 01955 a2200541 4500
005 20250517173117.0
264 0 _c20171030
008 201710s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/acs.jmedchem.7b00462
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMould, Daniel P
245 0 0 _aDevelopment of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_c10 2017
300 _a7984-7999 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aBiomarkers
650 0 4 _aCell Line, Tumor
650 0 4 _aComputer Simulation
650 0 4 _aDrug Design
650 0 4 _aDrug Discovery
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aEther-A-Go-Go Potassium Channels
_xdrug effects
650 0 4 _aGlycine
_xanalogs & derivatives
650 0 4 _aHigh-Throughput Screening Assays
650 0 4 _aHistone Demethylases
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aLeukemia
_xdrug therapy
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Docking Simulation
650 0 4 _aSpiro Compounds
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTranylcypromine
_xanalogs & derivatives
700 1 _aAlli, Cristina
700 1 _aBremberg, Ulf
700 1 _aCartic, Sharon
700 1 _aJordan, Allan M
700 1 _aGeitmann, Matthis
700 1 _aMaiques-Diaz, Alba
700 1 _aMcGonagle, Alison E
700 1 _aSomervaille, Tim C P
700 1 _aSpencer, Gary J
700 1 _aTurlais, Fabrice
700 1 _aOgilvie, Donald
773 0 _tJournal of medicinal chemistry
_gvol. 60
_gno. 19
_gp. 7984-7999
856 4 0 _uhttps://doi.org/10.1021/acs.jmedchem.7b00462
_zAvailable from publisher's website
999 _c27547699
_d27547699