000 01341 a2200373 4500
005 20250517173027.0
264 0 _c20191004
008 201910s 0 0 eng d
022 _a1179-1926
024 7 _a10.1007/s40262-017-0596-3
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCerruti, Lena
245 0 0 _aSemi-Mechanistic Model for Predicting the Dosing Rate in Children and Neonates for Drugs Mainly Eliminated by Cytochrome Metabolism.
_h[electronic resource]
260 _bClinical pharmacokinetics
_c07 2018
300 _a831-841 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdolescent
650 0 4 _aChild
650 0 4 _aChild, Preschool
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aDatabases, Factual
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHumans
650 0 4 _aInfant
650 0 4 _aInfant, Newborn
650 0 4 _aMetabolic Clearance Rate
_xdrug effects
650 0 4 _aModels, Theoretical
650 0 4 _aPharmaceutical Preparations
_xadministration & dosage
650 0 4 _aPredictive Value of Tests
700 1 _aBleyzac, Nathalie
700 1 _aTod, Michel
773 0 _tClinical pharmacokinetics
_gvol. 57
_gno. 7
_gp. 831-841
856 4 0 _uhttps://doi.org/10.1007/s40262-017-0596-3
_zAvailable from publisher's website
999 _c27544763
_d27544763