000 02029 a2200565 4500
005 20250517172508.0
264 0 _c20180521
008 201805s 0 0 eng d
022 _a2047-9980
024 7 _a10.1161/JAHA.117.006347
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChen, Ming-Liang
245 0 0 _aTrimethylamine-N-Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3-SOD2-mtROS Signaling Pathway.
_h[electronic resource]
260 _bJournal of the American Heart Association
_c09 2017
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAntioxidants
_xpharmacology
650 0 4 _aApoptosis Regulatory Proteins
_xmetabolism
650 0 4 _aAtherosclerosis
_xchemically induced
650 0 4 _aCells, Cultured
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFemale
650 0 4 _aGenetic Predisposition to Disease
650 0 4 _aHuman Umbilical Vein Endothelial Cells
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInflammasomes
_xagonists
650 0 4 _aInflammation Mediators
_xmetabolism
650 0 4 _aMethylamines
_xtoxicity
650 0 4 _aMice, 129 Strain
650 0 4 _aMice, Knockout, ApoE
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aNLR Family, Pyrin Domain-Containing 3 Protein
_xagonists
650 0 4 _aPhenotype
650 0 4 _aRNA Interference
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSirtuin 3
_xdeficiency
650 0 4 _aSuperoxide Dismutase
_xmetabolism
650 0 4 _aTime Factors
650 0 4 _aTransfection
650 0 4 _aVasculitis
_xchemically induced
700 1 _aZhu, Xiao-Hui
700 1 _aRan, Li
700 1 _aLang, He-Dong
700 1 _aYi, Long
700 1 _aMi, Man-Tian
773 0 _tJournal of the American Heart Association
_gvol. 6
_gno. 9
856 4 0 _uhttps://doi.org/10.1161/JAHA.117.006347
_zAvailable from publisher's website
999 _c27527197
_d27527197