000 02400 a2200613 4500
005 20250517170820.0
264 0 _c20181120
008 201811s 0 0 eng d
022 _a1740-634X
024 7 _a10.1038/npp.2017.177
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYoussef, Eriene A
245 0 0 _aEffect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results.
_h[electronic resource]
260 _bNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
_c02 2018
300 _a503-512 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aDNA Methylation
650 0 4 _aDouble-Blind Method
650 0 4 _aExcitatory Amino Acid Antagonists
_xadverse effects
650 0 4 _aFemale
650 0 4 _aFragile X Mental Retardation Protein
_xgenetics
650 0 4 _aFragile X Syndrome
_xdrug therapy
650 0 4 _aHumans
650 0 4 _aImidazoles
_xadverse effects
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aPsychotropic Drugs
_xadverse effects
650 0 4 _aPyridines
_xadverse effects
650 0 4 _aRNA, Messenger
_xblood
650 0 4 _aReceptor, Metabotropic Glutamate 5
_xantagonists & inhibitors
650 0 4 _aTreatment Failure
650 0 4 _aYoung Adult
700 1 _aBerry-Kravis, Elizabeth
700 1 _aCzech, Christian
700 1 _aHagerman, Randi J
700 1 _aHessl, David
700 1 _aWong, Chin Y
700 1 _aRabbia, Michael
700 1 _aDeptula, Dennis
700 1 _aJohn, Amy
700 1 _aKinch, Russell
700 1 _aDrewitt, Philip
700 1 _aLindemann, Lothar
700 1 _aMarcinowski, Moritz
700 1 _aLangland, Rachel
700 1 _aHorn, Carsten
700 1 _aFontoura, Paulo
700 1 _aSantarelli, Luca
700 1 _aQuiroz, Jorge A
773 0 _tNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
_gvol. 43
_gno. 3
_gp. 503-512
856 4 0 _uhttps://doi.org/10.1038/npp.2017.177
_zAvailable from publisher's website
999 _c27473507
_d27473507